“Postpartum depression is much more common than most people think,” says Dr. Samantha Meltzer-Brody, director of the Perinatal Psychiatry Program in the UNC Center for Women’s Mood Disorders. “The most important thing is for women to recognize they need professional … Continue reading
In recent studies published in Biological Psychiatry and Journal of Psychiatric Research (PMID 17367867 and 20122536), Center researchers identified variants in the estrogen receptor alpha gene that are associated with both PMS and psychological traits seen to differ in PMS.
This study in perimenopausal women examines the effects of stress reactivity, history of depression, and insulin sensitivity on the ability of estrogen replacement to decrease the risk of cardiovascular disease and depression. The grant was awarded on July 1st, and the study will occur over the next five years. This study will examine potential mechanisms underlying the interactive contributions of stress and the perimenopause on heart disease and mood dysregulation. Continue reading